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Radiation biology - effects of ionising radiation, radiosensitivity

BfS co-operation on "Radiobiology – effects of ionising radiation, radiosensitivity" with national and international partners

Co-operation within the scope of a European Network of biological dosimetryshow / hide

Co-operation partners

Objective

The goal of RENEB (Realizing the European Network of Biological Dosimetry) is to establish a sustainable European network in biological dosimetry involving 23 organisations from 16 European countries, that will guarantee highest efficiency in processing and scoring of biological samples for fast and reliable results implemented in the EU emergency management.

Co-operation focusing on individual levels of radiosensitivity (radiation research competence group KVSF)show / hide

Co-operation partners

Objective

Within the context of the project "Radiation-induced genomic instability: potential implications for radiosensitivity and the risk of cancer", epidemiological and molecular epidemiological research in the field of radiation and cancer is performed in partnership with the universities. One aspect of the project is the analysis of the BfS study on uranium miners for combined effects and research focussing on genetic factors.

Influence of long-term low-dose irradiation on cellsshow / hide

Co-operation partners

Objective

The effects of long-term low-dose irradiation are assessed at cellular level. The experimental test design is developed in collaboration with modelers in order to ensure optimum utilization of test results in mathematical models. The tests are first carried out using established cell lines and are then extended to stem cells (for fibroblasts or blood cells).

Co-operation focussing on targets and signalling pathways of radiation hypersensitivity and resistanceshow / hide

Co-operation partners from universities

Objective

The objective of this multidisciplinary project is to identify molecular targets and signalling pathways underlying cellular radiation hypersensitivity and resistance of tumour and normal tissue.

State of 2015.08.14

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